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Treatment of cervical intraepithelial neoplasia 2–3 and adenocarcinoma in situ: cryotherapy, large loop excision of the transformation zone, and cold knife conization : WHO guidelines

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Titre:      Treatment of cervical intraepithelial neoplasia 2–3 and adenocarcinoma in situ: cryotherapy, large loop excision of the transformation zone, and cold knife conization : WHO guidelines
Catégorie:      Cancer, Cancer cervical, Gynécologie, Santé de la femme, Livre
LivreID:      74
Auteurs:      Organisation Mondiale de la Santé
ISBN-10(13):      978-92-4-150677-9
Editeur:      Organisation Mondiale de la Santé
Date de publication:      2014
Number of pages:      34
Langue:      Anglais
Classification:      1 
Image:      cover
Livre électronique:      Télécharger 1.pdf
Télécharger 2.pdf
Description:     

Cervical intraepithelial neoplasia (CIN) is a premalignant lesion that is diagnosed by histology as CIN1, CIN2, or CIN3. If left untreated, CIN2 or CIN3 (collectively referred to as CIN2+) can progress to cervical cancer. There are three principal treatments for CIN available in low- and middle-income countries: cryotherapy, large loop excision of the transformation zone (LEEP), and cold knife conization (CKC).

This guideline builds upon the "WHO guidelines: use of cryotherapy for cervical intraepithelial neoplasia" published in 2011, and provides recommendations for the use of cryotherapy versus LEEP versus CKC for the treatment of histologically confirmed CIN2+, and additional recommendations for the treatment of histologically confirmed adenocarcinoma in situ (AIS).

Supplemental material
GRADE evidence-to-recommendation tables and evidence profiles for each recommendation

34 pages, livre accompagné d'une brochure

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